Mia has been in wool full time from birth and we haven't had any problems at all. I hate PUL wraps with a passion and pockets aren't great for absorbency or containment on a newborn so wool was the only option for us really. It doesn't take long to wash woollies so that wasn't really an issue here either.
But will be doing the washing anyway with clothes and nappies so the wool will be extra. I quite like washing wool though will be worth it I think I suppose its the idea of washing poo out of the wool I will just have to get over it how many woolies do you think ?
I think around 4-5 in each size probably, maybe less when you move into mediums. Washing poo out of woollies has never really bothered me but you can always use gloves if its an issue. I use Ewe Need It soap bars for scrubbing dirty woollies, then the woolly wash afterwards. And then either spray lanolin or solid lanolin depending on when they were last lanolised properly.
I'd go with wool as well except there's always the possibility that you might have a baby that's sensitive to wool/lanolin. I'd hate to be without any back-up plan if that happened! I've ordered some PUL wraps that were on clearance offer, and plan to start knitting a bit later on (not due until end Dec, so lots of time... she says!), and maybe buy a pre-made merino too.
Don't get me wrong, I'm a BIG wool and merino fan for me - I could wax lyrical about its virtues, but I like to have my bases covered!